Construction of tumor-specific toxins using ubiquitin fusion technique
نویسندگان
چکیده
منابع مشابه
Construction of a fusion protein carrying antigenic determinants of enteric clostridial toxins.
Clostridium difficile and Clostridium perfringens type A are infectious agents of enteric diseases. The main virulence factors of these microorganisms include toxins A and B of C. difficile (ToxA and ToxB) and enterotoxin of C. perfringens (Cpe). In this study genetic constructions have been created for the expression of ToxA, ToxB and Cpe fragments either as individual components or as a hybri...
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ژورنال
عنوان ژورنال: Molecular Therapy
سال: 2005
ISSN: 1525-0016
DOI: 10.1016/j.ymthe.2004.10.009